DENVER STEM CELL THERAPY
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At Denver Regenerative Medicine, we’re an early pioneer in providing Denver with advanced stem cell therapy treatments as alternatives to conventional intervention techniques. When appropriate, stem cell therapy injections in the knees, shoulders, and other joints may be a better option than surgery for many patients. There are many advantages to stem cell therapy at our Denver Regenerative Medicine clinic over surgery including faster recovery, less pain, lower cost, decreased or eliminated need to immobilize with a sling or cast and other benefits as well. Before any procedure takes place, we will meet with you for an initial consultation to evaluate your injuries and determine the best stem cell injection options for you.
WHAT ARE STEM CELLS?
Stem cells are self-renewing and can grow into any type of cell needed by your body. Our regenerative medicine clinic in Denver’s adult stem cell therapies use your own cells to create a customized treatment regimen that is readily accepted by your body. This can reduce the risk of rejection of these healing cells and can boost your own natural rejuvenating capabilities.
HOW DOES STEM CELL THERAPY WORK?
The stem cell therapy process involves several steps that must be followed in order:
• The extraction of stem cells from body fat, bone marrow or other tissue
• The conditioning of these cells to maximize their healing ability
• Injecting cells into joints and other areas where they can do the most good
This process may be repeated to boost the ability of stem cells to restore damaged cells and to increase mobility and comfort for our patients.
DENVER REGENERATIVE MEDICINE’S UNIQUE STEM CELL THERAPY PROCEDURE
Our experience using stem cells to treat our patients since 2012 has taught us that not all stem cells work the same way. Initially, we used bone-marrow-derived mesenchymal stem cells (MSC’s) along with platelets (PRP), both extracted and isolated from the patient’s own body, to inject into the injured or damaged joint, muscle, tendon, or bone. Our results were much better than we had originally anticipated, as patients who had exhibited the most severe bone-on-bone arthritis were able to avoid joint replacement surgery for many years following this procedure.
However, always wanting to find methods that produce the absolute greatest result in the shortest time, we looked at other types of stem cell extraction methods. One that had gained popularity in the past several years has the extraction and use of adipose or fat-based stem cells. Much like bone marrow, our abdominal fat contains millions of stem cells which can be isolated and injected back into the body to heal damaged tissue. These adipose-derived stem cells have the advantage of being available in much higher concentrations than bone-marrow-derived stem cells, and they also seem to promote soft tissue (ligament and muscle) much more efficiently than bone marrow-derived stem cells.1
So, for several years we had one provider who performed bone-marrow-derived stem cell procedures, and another who used only the fat-based adipose-derived stem cells. Both methods proved to be equally successful over time, with the fat-based adipose-derived stem cell procedure having the advantage of treating several areas of the body at the same time due to the high volume of stem cells present in adipose tissue (abdominal fat).
After 2 years of following these patients and comparing the outcomes, we decided that our new procedure would involve the use of both types of stem cells, adipose, and bone-marrow-derived. What we observed was that patients were getting better almost 30% faster than when only one type of stem cell was used. Further, these patients seemed to have a much stronger repair with much less residual pain and loss of function.
Because of these results, we always recommend using a patient’s own adipose-derived fat-based stem cells and bone-marrow-derived (MSC’s) stem cells. Before you decide on a specific stem cell procedure, make sure that you understand what types of cells are going to be used. If you are interested in our unique stem cell therapy procedure, please contact Denver Regenerative Medicine to schedule a consultation.
STEM CELL THERAPY AS AN ALTERNATIVE TO SURGERY
Joint replacement surgery involves the amputation of the biological joint and replacement with a synthetic prosthesis. Stem cell therapy treatment for joints has advanced considerably to give us sophisticated alternatives to joint replacement surgery. Joint replacement surgery is very difficult and painful and can result in negative long-term side effects.
The risks of joint prostheses include higher heart attack and stroke risk, absorbed prostheses metals and particulates into the bloodstream and of course, the removal of a natural joint to replace with an artificial joint. Denver Stem Cell therapy treatments for the knees and other joints at our medical clinic actually target the damaged cell tissues with specially programmed stem cells taken from your adipose tissue (fat cells). These cells are programmed to intervene within damaged tissues and regenerate healthy cells. This can dramatically improve the function of the joint, resulting in increased mobility, decreased pain, and overall better quality of life. All of our stem cell therapy treatments are completed without high impact surgical interventions.
DONOR STEM CELLS, UMBILICAL STEM CELLS, CORD BLOOD, & REGENERATIVE MEDICINE PROCEDURES vs. AUTOLOGOUS (YOUR OWN) STEM CELLS
In recent years there has been a proliferation of clinics claiming to perform stem cell procedures using a variety of produces that are now widely available. These products include donor umbilical stem cells, cord blood stem cells, Wharton’s Jelly, exosomes, etc. All of these products are extracted from donors’ and then grown in a laboratory setting. While these products do have some very positive healing properties, they do not match the power of using your own stem cells.2
Because it is necessary to have a board-certified medical doctor perform the extraction procedure to remove a patient’s own autologous stem cells, many clinics only offer donor stem cell or regenerative medical procedures. They will often suggest that a patient’s own stem cells are too old to be effective and that donor cells are newer and will thusly work better. This could not be further from the truth; nothing works better in your own body than your own stem cells! Most commonly, these clinics do not have a board-certified MD on staff to perform the extraction procedure properly.
|DONOR STEM CELLS vs. AUTOLOGOUS (your own) STEM CELLS|
|Donor Stem Cells||Autologous Stem Cells|
|Come Frozen and more than 50% lost in thawing||Freshly harvested, close to 100% viable cells|
|Chance of rejection by immune system||Same body, no chance of rejection|
|Produced in a laboratory||Made by your own body|
|Chance of contamination||No contamination possible|
|May not be compatible||Always compatible|
|No FDA approval||Autologous stem cell procedure approved|
In addition to these factors, there have been incidences of donor (umbilical cord) stem cell contamination by some companies producing their products, with grave health concerns for patients receiving those products. Here is a recent article. If you are interested in learning more about our autologous stem cell procedures, please call or schedule a consultation with Denver Regenerative Medicine online.3
WHAT TYPES OF STEM CELL THERAPIES ARE THERE?
The stem cell therapies available from Denver Regenerative Medicine can be used to treat deterioration of the joints of the knees, elbows, shoulders, and hips and to boost healing for soft tissues. Our medical team uses the latest methods and the most advanced technologies to ensure that you receive the best Denver stem cell therapy for your knee, joint and shoulder pain or other medical needs. This can help you to avoid joint replacement surgery and the complications these procedures can sometimes entail.
1 “Comparison of Human Adipose-Derived Stem cells and Bone Marrow-Derived Stem Cells in a Myocardial Infarction Model”
Jeppe Grøndahl Rasmussen, Ole Frøbert, Claus Holst-Hansen
2 “Autologous vs. Allogenic Stem Cell Transplants: What’s the Difference?”
Published: March 6, 2017, Updated: November 11, 2019
Medically Reviewed By: Joseph H. Antin, MD
3 “Stem Cells: Past, Present, and Future”
Stem Cell Research & Therapy volume 10, Article number: 68 (2019)
Wojciech Zakrzewski, Maciej Dobrzyński, Maria Szymonowicz & Zbigniew Rybak